Yes, you can apply to two recruiting studies linked to cleaning-product reactions. The NIH Clinical Center lists NIAID's THREAT trial as recruiting healthy adults ages 18-80 to test everyday exposures including cleaning and hygiene products THREAT trial listing.
Contact dermatitis is an itchy, swollen skin reaction to an allergen or irritant. The Cleveland Clinic lists detergents, soap, cleaners and acids among common irritants that can trigger it contact dermatitis overview. That distinction matters because the two studies enroll different people.
Official resources:
- Check eligibility on NIH’s official study page — Use this page to check the study’s participation requirements.
- Register through Veeva’s official page — Use this page to review requirements and register directly.
Table of Contents
- What does the THREAT trial study?
- What does participation involve?
- Who fits THREAT, and who likely does not?
- Is there a study for existing rashes?
- How do you apply?
What does the THREAT trial study?
THREAT stands for Testing Harms Related to Exposure to Allergenic and Epithelial Toxins. It tests whether everyday exposures affect allergic and inflammatory responses. Cleaning, hygiene and other products are among the exposures studied.
One hospital stay uses a pure room with filtered air, unprocessed foods and low-chemical personal-care products. The other stay uses real-world soaps, shampoos, processed diet and air exposures, assigned by skin, gut or airway cohort with crossover. ClinicalTrials.Veeva for the NIAID sponsor describes that pure-room comparison and crossover design THREAT study design.
What does participation involve?
Participants complete two confined 7-day hospital stays spaced 4 to 6 weeks apart. Each stay is followed by an outpatient visit about 2 weeks later. The NIH Clinical Center says the schedule includes blood, skin-cell, urine, mouth-swab and stool samples plus lung, smell and skin-health tests.
That means about 14 confined inpatient days on assigned foods and products, plus follow-ups. Applicants need sustained availability for confinement. Travel and daily routine must fit two separate week-long admissions.
Who fits THREAT, and who likely does not?
THREAT enrolls only healthy volunteers ages 18-80. The NIH Clinical Center excludes non-English speakers, pregnant people, children, neonates, fetuses and adults unable to consent.
People with active severe cleaning-product allergy may not qualify. Use this quick check before applying: If any answer is no, the rash-focused program below may fit better.
- Are you 18-80 and generally healthy?
- Can you stay in hospital for 7 days, twice?
- Can you follow assigned foods, soaps and air conditions?
- Do you meet language, pregnancy and consent rules?
Is there a study for existing rashes?
Yes. A separate active contact-dermatitis program invites adults over 18 with contact-dermatitis history or allergic rash. Applicants start with an online questionnaire.
Cleaning products are named among the common allergens screened. The program tests a medication-free non-steroid cream. Study care is provided at no cost, with time and travel compensation. AutoCruitment lists the questionnaire, cream test and compensation terms contact-dermatitis study invitation.
How do you apply?
Confirm the listed eligibility first, then use that trial's contact and location channel. For THREAT, include your age, health status, language, availability for both 7-day stays and follow-up visits.
For the rash program, describe your contact-dermatitis history, rash triggers and prior treatments. Availability for confinement is the main practical filter for THREAT applicants.
